Systemic intoxication can be caused by absorption through the skin or by inhalation.

Systemic intoxication can be caused by absorption through the skin or by inhalation.

• A. It can occur only through skin absorption.
• B. It can be caused by absorption through the skin or by inhalation.
• C. It occurs only through ingestion.
• D. It is unrelated to route of exposure.

Answer: (B)

Systemic intoxication happens when a chemical gets into the bloodstream and affects organs away from where it contacted you. It can occur by absorption through the skin because some substances can penetrate the skin and enter circulation, and by inhalation because the lungs provide a rapid path for vapors, aerosols, or dust to pass into the blood. Whether a chemical causes systemic effects via these routes depends on properties like volatility and skin permeability, so both pathways are important to consider in exposure assessment and control. Ingestion is another route that can cause systemic effects, but it’s not the only route, and saying there’s no relation to the exposure route would be incorrect.

Systemic intoxication happens when a chemical gets into the bloodstream and affects organs away from where it contacted you. It can occur by absorption through the skin because some substances can penetrate the skin and enter circulation, and by inhalation because the lungs provide a rapid path for vapors, aerosols, or dust to pass into the blood. Whether a chemical causes systemic effects via these routes depends on properties like volatility and skin permeability, so both pathways are important to consider in exposure assessment and control. Ingestion is another route that can cause systemic effects, but it’s not the only route, and saying there’s no relation to the exposure route would be incorrect.